April 19, 2023
Application scenario of single-use storage bags and stainless steel bioreactor:
1,
Single-use storage bags can be used as the lining of a stainless steel
bioreactor, avoiding the steps of cleaning, disinfection and validation,
improving the flexibility and efficiency of the bioprocess. This method
is suitable for pilot scale and small scale manufacturing processing,
especially for multi-product or multi-batch production.
2,
Single-use storage bags can be used as pre-or post-equipment for
stainless steel bioreactor for cell culture or microbial fermentation
seed culture, buffer preparation, medium preparation, harvesting,
concentration or purification processes. In this way, the frequency and
quantity of stainless steel bioreactor can be reduced, and the cost and
risk can be reduced.
3, Single-use storage bags can form a mixed
system with stainless steel bioreactors for cell culture or microbial
fermentation at different stages or scales. This approach allows
flexible and efficient bioprocesses to take advantage of the high
pressure steam sterilization and cleaning capabilities of stainless
steel bioreactors and the rapid replacement and low maintenance
advantages of disposable biotreatment bags.
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